Conclusion Retatrutide and Mounjaro are both impressive for weight loss and blood sugar control
In real-world clinical practice, average outcomes vary based on individual factors including starting weight, adherence, dose achieved, lifestyle support, and presence of comorbidities
However, users should be aware of the potential variability due to nasal membrane condition, congestion, or improper administration technique
Most users continue to lose weight throughout their first year of treatment, but the rate of weight loss often slows from months 6-12
The mechanism of action centers on mimicking endogenous GLP-1, an incretin hormone naturally released from intestinal L-cells following food intake